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Tainted Heparin Shines Light on Funding-Starved FDA's Inability to Protect USA Drug Supply

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John Moffett
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Now that the contaminant has been identified it becomes much simpler to outline a possible scenario for what happened. It is not known if the pig farmers who collected the pig intestines and processed the crude heparin extracts could have known enough to have produced the contaminant. However, it would be a simple matter of reacting the cartilage extract with sulfuric acid in order to increase the sulfur content to that found in heparin. It may be some time before we find out which portion of the supply chain from crude extracts to finished heparin that batches were spiked with highly sulfated chondroitin sulfate, but it is virtually impossible that this could have happened accidentally. To my knowledge there is no possible commercial use for sulfated chondroitin sulfate except that it would have heparin-like properties and be difficult to differentiate from real heparin. That is until it was injected into human patients, many of whom became extremely ill, while some became so ill they died.

The F.D.A. has received over 785 reports of injuries and serious adverse reactions associated with the use of tainted heparin in the US, with at least 19 deaths attributed to the contaminated blood thinner. As reported by the Washington Post, a series of independent assessments, including one by the FDA’s own Science Board, have found that the FDA is increasingly overwhelmed by its responsibilities, and is no longer capable of protecting the public from unsafe drugs and food, particularly those coming from China. There is a growing consensus on Capitol Hill that the FDA needs a rapid infusion of money if it is to protect the US food and drug supplies. Based on recent stories of toxic pet food, lead-filled children’s toys, and toxic pharmaceuticals, that is probably an understatement.

Final note: The US government under George Bush is spending billions of dollars a week to supposedly protect you from terrorism, while at the same time spending far, far less to protect American’s food and drug supplies. Obviously, the government’s priorities are not matched to the realities of our modern, globalized world.

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John R. Moffett PhD is a research neuroscientist in the Washington, DC area. Dr. Moffett's main area of research focuses on the brain metabolite N-acetylaspartate, and an associated genetic disorder known as Canavan disease.

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