One could imagine a situation where Obama supports a piece of legislation or nominates someone that Lieberman and both the conservative and moderate Republicans cannot tolerate. In that case, it would make sense for the Republicans to try to convince eight conservative or moderate Democrats to join them in voting down the measure/person. It is hard to imagine an issue or person where they would not be able to find eight Democrats to join them and would instead be able to organize a successful filibuster.
Obama may be defeated in some of his proposals by a coalition of Republicans and Democrats, but it is unlikely the Republicans will attempt to filibuster any of them. The magical incantation "filibuster" is a charm without real power or effect, just an illusion piously prayed for by disturbed minds..
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