To use scopolamine most effectively to get a prisoner to tell you what he or she knows, the key is where you inject it, and in what amounts. Normally it is introduced into the body by a transdermal patch or intravenously in the arm. However, if you inject it into the spine (amount classified), it causes absolutely incredible pain, accompanied by violent convulsions and seizures. If injected into the spine in the appropriate amount, more than 95% of all prisoners will tell the truth -- not something fabricated to stop the pain -- within 24 hours (Source: classified).
A far milder form of psychological abuse involves exposing prisoners (intravenously or orally) to sodium pentathol—commonly known as "truth serum." Sodium pentathol is an ultra-short-acting barbiturate that depresses the central nervous system, slows heart rate, and lowers blood pressure. In the relaxed state produced by the drug, subjects are more susceptible to suggestion and are therefore easier to interrogate. The drug does not actually guarantee that prisoners will tell the truth, however. Often, it makes subjects "gabby" without revealing any important information.
Sodium amythal, also known as a type of "truth serum," with its clinical application in psychoanalysis, is used primarily to help in memory recovery and dealing with "false" memories. If you can confuse the prisoner as to what is a real memory and what is a false memory, you might be able to crack their resistance to telling the truth. However, if the prisoner is smart, he or she will simply shut up and you'll get nothing from them.
What is interesting is that a prisoner could have been subjected to a truth serum singularly, or two or three over enough time given the appropriate washout of the prisoner's system, and flatly state that he or she did not tell his or her interrogators anything. From his or her perspective, he or she is telling the
truth -- because he or she has no memory of telling interrogators anything. That's the truth in his or her own mind, but it is not the fact of the situation.
In terms of training individuals to resist the three aforementioned truth serums, it is easiest to train someone to resist the sodium amythal, followed by sodium pentathol. There is no known training that will allow anyone to resist scopolamine, when injected into the spine in the correct amount.
What you don't want to do is "stack" scopolamine with sodium pentathol and sodium amythal. "Stacking" means adding one drug on top of another before the previous drug(s) has/have washed out of the system. You stack on somebody, you'll kill them.
When time is not a consideration, and when used in conjunction with skilled interrogators on a prisoner who has not been trained to resist the effects, sodium pentathol and sodium amythal will get you the truth in approximately 10% to one third of the cases. When the truth absolutely positively has to be there within five days, forget them – use scopolamine injected into the spine.
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